| Name | Phone | Category |
| Taco John's | (515) 964-9800 | Restaurants |
| Tailgate Clothing Company | (515) 963-7903 | Wholesale |
| Tailored Travel, Inc. | (866) 923 9050 | Travel |
| Tanworld - Ankeny | (515) 965-3985 | Health & Beauty |
| Tasteful Dinners/Tasteful Catering | (515) 965-3324 | Food-Beverage |
| Tastefully Simple | (515) 971-6612 | Independent Consultant |
| The Tavern Restaurant | (515) 223-6700 | Restaurants |
| Teegos Lawn Service | (515) 720-3497 | Lawn Maintenance |
| Tender Years Day Care Center | (515) 964-5437 | Day Care |
| Texaco Xpress Lube | (515) 965-9122 | Automotive |
| Texas Roadhouse | (515) 251-4597 | Restaurants |
| Textbook Outlet | (515) 965-4238 | Education |
| Therapeutic Massage Center - Beth Madison | (515) 669-3366 | Health Care |
| Therapeutic Massage Center - Megan Sams | (515) 964-3934 | Health Care |
| Thornton & Coy Law Office, PLC | (515) 964-1825 | Legal Services |
| Thorpe Water Development Company | (515) 289-2345 | Utilities |
| Tim's bp/Amoco Service | (515) 964-9645 | Automotive |
| Tin Cup Bar & Grill | (515) 965-6462 | Restaurants |
| Tires Plus | (515) 963-4040 | Automotive |
| TNT Landscaping & Nursery | (515) 965-1206 | Design Services |
| Tokyo Steakhouse | (515) 963-8898 | Restaurants |
| Tonic | (515) 965-5423 | Entertainment-Recreation |
| Tournament Club of Iowa | (515) 984-9440 | Entertainment-Recreation |
| Toyota Scion of Des Moines | (515) 276-4911 | Automotive |
| Tractor Supply Co. | (515) 965-8774 | Retail-Shops-Stores |
| Treasure House | (515) 964-0600 | Retail-Shops-Stores |
| TreeHouse Growing and Learning Center | (515) 965-5505 | Education |
| Triad Kids Campus | (515) 963-0215 | Entertainment-Recreation |
| Tri-County Boarding Kennel | (515) 685-4497 | Animal |
| Tucker Law Office | (515) 276-8282 | Legal Services |
| Tuffy Auto Service Center | (515) 965-5570 | Automotive |
| Turning Leaf Interiors | (515) 229-6722 | Design Services |
| Twisted Entertainment | (515) 509-1993 | Entertainment-Recreation |
| Two Men and A Truck | (515) 276-7170 | Moving |
| Two Rivers Bank & Trust | (515) 964-2265 | Finance |
| Two Rivers Insurance Services | (515) 963-9301 | Insurance-Finance |