| Name | Phone | Category |
| Eagle Sign Company | (515) 243-5663 | Retail-Shops-Stores |
| Easter Seals Child Development Center | (515) 289-1933 | Day Care |
| Easter Seals Iowa | (515) 309-9777 | Organizations |
| Edge Commercial | (515) 221-1660 | Contractor |
| Edward Jones Investments - Brian Herbel, AAMS, CFP | (515) 964-1010 | Finance |
| Edward Jones Investments - Kevin Fisher | (515) 964-1841 | Finance |
| Edward Jones Investments - Terry Peter | (515) 965-6901 | Finance |
| Edward Jones Investments - Tracy Burt | (515) 964-4404 | Finance |
| Elite Fleet Lawn Care | (515) 339-1987 | |
| Embria Health Sciences, LLC | (515) 963-9100 | Health Care |
| Encore Dance Academy | (515) 974-4074 | Dance |
| Energy Doctor, Inc. | (515) 963-9681 | Contractor |
| Enterprise Rent A Car | (515) 963-9300 | Automotive |
| Envision Salon Spa | (515) 964-4009 | Health & Beauty |
| Epilepsy Foundation of North/Central IL., IA. & NE | (515) 238-7660 | Organizations |
| Exec 1 Aviation | (515) 965-1020 | Transportation |
| Exhibits & Displays, Inc. | (515) 263-8435 | Business Services |
| Expressions by Em | (515) 836-8276 | Design Services |
| Eyecare Associates of Ankeny | (515) 964-7355 | Health Care |
| Eyecare Associates of Ankeny - Dr. Jim Schroder | (515) 964-7355 | Health Care |